Yes, St. John’s Wort has a calming effect on the mind. Some studies have shown that it is effective for mild and moderate depression and has less side effects than prescription medicines. A word of caution, though: If you are taking prescription medicines, St. John’s Wort can cause many not to be as effective. You would not want to take St. John’s Wort without consulting your health care professional in that case. Also, if you are taking birth control pills, St. John’s Wort can cause them not to be as effective. Taking St. John’s Wort while on birth control pills is not recommended.